Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607492 | 0.87 | POLB (0.43) | KMT2AABL1EPHX2TRPV1PPARA | |
| SCHEMBL8515651 | 0.85 | KMT2A (0.48) | KMT2AEPHX2FAAHTRPV1NLRP3 | |
| SCHEMBL9607090 | 0.78 | PDE2A (0.42) | KMT2AABL1EPHX2PPARANPC1 | |
| SCHEMBL8537891 | 0.77 | EPHX2 (0.51) | KMT2AABL1EPHX2NPC1RAB9A | |
| SCHEMBL9607414 | 0.74 | TRPV1 (0.47) | KMT2AABL1EPHX2TRPV1PPARA | |
| SCHEMBL9607506 | 0.74 | EPHX2 (0.45) | EPHX2FAAHTRPV1PPARANPC1 | |
| SCHEMBL9607091 | 0.74 | EPHX2 (0.45) | EPHX2FAAHTRPV1PPARANPC1 | |
| SCHEMBL508864 | 0.68 | MRGPRX4 (0.57) | KMT2AEPHX2FAAHTRPV1NPC1 | |
| SCHEMBL10874020 | 0.66 | KMT2A (0.62) | KMT2AEPHX2FAAHTRPV1NPC1 | |
| SCHEMBL10874014 | 0.66 | KMT2A (0.62) | KMT2AEPHX2FAAHTRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |