Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515814 | 1.00 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15668053 | 0.73 | — | — | |
| SCHEMBL15668056 | 0.73 | — | — | |
| SCHEMBL8947046 | 0.72 | — | — | |
| SCHEMBL3829643 | 0.72 | CES2 (0.44) | ALDH1A1 | |
| SCHEMBL30921916 | 0.71 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL6055330 | 0.71 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL8515809 | 0.69 | BTN3A1 (0.36) | ALDH1A1 | |
| SCHEMBL16934916 | 0.67 | TSHR (0.38) | ALDH1A1 | |
| SCHEMBL8625523 | 0.67 | BTN3A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071458-A1 | HETEROCYCLIC INHIBITORS OF BETA - SECRETASE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-05-31 | — | — | WO | disclosed |