Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947046 | 0.86 | — | — | |
| SCHEMBL2582810 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL10906327 | 0.74 | — | — | |
| SCHEMBL15292867 | 0.74 | ADRB2 (0.38) | — | |
| SCHEMBL8473354 | 0.74 | — | — | |
| SCHEMBL8473356 | 0.74 | — | — | |
| SCHEMBL2599066 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL8947094 | 0.73 | BTN3A1 (0.34) | BTN3A1 | |
| SCHEMBL8849600 | 0.73 | BTN3A1 (0.34) | BTN3A1 | |
| SCHEMBL8896843 | 0.73 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |
| US-5470845-A | Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-11-28 | — | — | US | disclosed |