Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819011 | 0.89 | HPGD (0.65) | MEN1KMT2AHPGDTDP1TTR | |
| SCHEMBL28053101 | 0.83 | MEN1 (0.50) | MEN1KMT2AHPGDTDP1TTR | |
| SCHEMBL8515928 | 0.80 | RHEB (0.46) | MEN1KMT2AHPGDTTRMAPT | |
| SCHEMBL11100238 | 0.80 | MEN1 (0.59) | MEN1KMT2AHPGDTDP1TTR | |
| SCHEMBL15330302 | 0.80 | PDE7A (0.52) | MEN1KMT2AHPGDTDP1TTR | |
| SCHEMBL11819831 | 0.80 | MEN1 (0.52) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL8512098 | 0.79 | MEN1 (0.44) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL15329532 | 0.78 | HSPB1 (0.58) | MEN1KMT2AHPGDTDP1MAPT | |
| SCHEMBL15330045 | 0.78 | HSPB1 (0.55) | MEN1KMT2AHPGDTDP1TTR | |
| SCHEMBL15340938 | 0.78 | TSHR (0.54) | MEN1KMT2AHPGDTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053585-B | Synthetic method of triclabendazole | 暨明医药科技（苏州）有限公司 | 2020-10-23 | — | — | CN | claimed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | claimed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | claimed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | claimed |
| CN-109053585-B | Synthetic method of triclabendazole | 暨明医药科技（苏州）有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-109053585-B | Synthetic method of triclabendazole | 暨明医药科技（苏州）有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-103360323-B | Preparation method of triclabendazole | Changzhou jialing medicine industry co ltd | 2014-07-09 | — | — | CN | disclosed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | disclosed |
| CN-103360323-A | Preparation method of triclabendazole | Changzhou jialing medicine industry co ltd | 2013-10-23 | — | — | CN | disclosed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012070068-A3 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-07-19 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| US-5322853-A | For controlling or preventing an attack on plants by phytopathogenic microorganisms | CIBA-GEIGY CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0462931-B1 | Benzotriazole-1-sulfonyl derivatives with microbicidal properties | CIBA GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| EP-0462931-A1 | Benzotriazole-1-sulfonyl derivatives with microbicidal properties | CIBA-GEIGY AG (CH) | 1991-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | NIT2, CA3, TET3 | MEN1 1675/4885KMT2A 455/4885HPGD 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.