Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515941 | 1.00 | GPR52 (0.47) | GPR52KMT2ANPC1RAB9ACA12 | |
| SCHEMBL16658710 | 0.89 | GPR52 (0.46) | GPR52KMT2A | |
| SCHEMBL9608627 | 0.83 | GPR52 (0.41) | GPR52KMT2A | |
| SCHEMBL16658714 | 0.81 | ALOX5 (0.43) | GPR52KMT2A | |
| SCHEMBL16658717 | 0.80 | ALOX5 (0.46) | KMT2A | |
| SCHEMBL17715346 | 0.79 | GPR52 (0.41) | GPR52 | |
| SCHEMBL16658731 | 0.79 | TRPV1 (0.46) | — | |
| SCHEMBL16658719 | 0.79 | TRPV1 (0.46) | — | |
| SCHEMBL16658789 | 0.78 | GPR52 (0.51) | GPR52 | |
| SCHEMBL16658781 | 0.75 | GPR52 (0.51) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |