Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515939 | 0.83 | GPR52 (0.47) | GPR52KMT2A | |
| SCHEMBL8515941 | 0.83 | GPR52 (0.47) | GPR52KMT2A | |
| SCHEMBL16658710 | 0.82 | GPR52 (0.46) | GPR52KMT2A | |
| SCHEMBL7458715 | 0.79 | MLYCD (0.50) | HTR2CSLC6A4L3MBTL1KMT2ACTSK | |
| SCHEMBL9608852 | 0.76 | SIGMAR1 (0.46) | GPR52CTSKCTSSCTSLCTSB | |
| SCHEMBL7190668 | 0.75 | RIPK1 (0.57) | HTR2CSLC6A4KMT2AGLSCTSS | |
| SCHEMBL6824553 | 0.75 | GPR52 (0.55) | GPR52 | |
| SCHEMBL6824556 | 0.75 | GPR52 (0.55) | GPR52 | |
| SCHEMBL16658714 | 0.74 | ALOX5 (0.43) | GPR52KMT2A | |
| SCHEMBL9358204 | 0.73 | LTB4R (0.49) | HTR2CSLC6A4L3MBTL1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |