Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777441 | 0.85 | CYP1A2 (0.43) | CYP1A2BRAFKDM4EALDH1A1NPC1 | |
| SCHEMBL3787255 | 0.84 | MAP4K4 (0.45) | CYP1A2KDM4EALDH1A1NPC1HPGD | |
| SCHEMBL8777438 | 0.84 | MAP4K4 (0.45) | CYP1A2KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL8777447 | 0.84 | LMNA (0.41) | GAACYP1A2KDM4EALDH1A1NPC1 | |
| SCHEMBL8777470 | 0.84 | ALDH1A1 (0.52) | CYP1A2KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL8777408 | 0.81 | P2RX3 (0.42) | CYP1A2KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL8777503 | 0.81 | MAP4K4 (0.48) | GAACYP1A2KDM4EALDH1A1LMNA | |
| SCHEMBL8777472 | 0.81 | MRGPRX1 (0.36) | CYP1A2KMT2AALOX5APFEN1 | |
| SCHEMBL3786821 | 0.81 | HTT (0.47) | CYP1A2KDM4EALDH1A1NPC1LMNA | |
| SCHEMBL8515946 | 0.80 | KDM4E (0.43) | CYP1A2KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |