Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 7/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516671 | 0.89 | CAMK2D (0.35) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7657926 | 0.89 | USP2 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL8516330 | 0.88 | TP53 (0.42) | AVPR1BSERPINE1ICMTPOLB | |
| SCHEMBL8516587 | 0.87 | F2RL3 (0.42) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7666306 | 0.86 | USP2 (0.39) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7662061 | 0.86 | POLB (0.38) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516843 | 0.85 | CAMK2D (0.49) | KDR | |
| SCHEMBL7660922 | 0.85 | PDE4A (0.37) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7652540 | 0.85 | PDE4A (0.37) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516327 | 0.85 | CAMK2D (0.46) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |