Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 11/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516339 | 0.94 | F2RL3 (0.44) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516409 | 0.89 | TP53 (0.43) | POLBTP53 | |
| SCHEMBL8516249 | 0.87 | F2RL3 (0.40) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7657926 | 0.85 | USP2 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL8516793 | 0.85 | CAMK2D (0.48) | — | |
| SCHEMBL8516977 | 0.84 | CAMK2D (0.46) | — | |
| SCHEMBL7662061 | 0.83 | POLB (0.38) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7666306 | 0.83 | USP2 (0.39) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7660922 | 0.82 | PDE4A (0.37) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7652540 | 0.82 | PDE4A (0.37) | F2RL3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |