Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516249 | 0.89 | F2RL3 (0.40) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7662878 | 0.89 | ACKR3 (0.36) | CAMK2DACKR3PDE4APDE4BPDE4C | |
| SCHEMBL8516843 | 0.85 | CAMK2D (0.49) | CAMK2DCNR1 | |
| SCHEMBL7656864 | 0.85 | ACKR3 (0.34) | ACKR3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7664754 | 0.85 | ACKR3 (0.34) | ACKR3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516327 | 0.85 | CAMK2D (0.46) | CAMK2DCNR1 | |
| Acetic Acid SCHEMBL8516673 | 0.81 | CAMK2D (0.37) | CAMK2DACKR3PDE4APDE4BPDE4C | |
| SCHEMBL7654522 | 0.78 | ALDH1A1 (0.42) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8365260 | 0.78 | CAMK2D (0.41) | CAMK2D | |
| SCHEMBL8516330 | 0.78 | TP53 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |