Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | GALR3 | O60755 | 1/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515901 | 0.85 | HTT (0.65) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8506195 | 0.85 | HTT (0.58) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1904097 | 0.84 | HTT (0.70) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9609170 | 0.82 | HTT (0.61) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8496629 | 0.82 | HTT (0.71) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8515790 | 0.82 | LMNA (0.58) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8498550 | 0.81 | MEN1 (0.63) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8498537 | 0.81 | MEN1 (0.56) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8504041 | 0.79 | HTT (0.74) | HTTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8516166 | 0.79 | HTT (0.77) | HTTLMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |