Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | GALR3 | O60755 | 2/20 | 0.65 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516267 | 0.85 | HTT (0.61) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8496629 | 0.85 | HTT (0.71) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1904097 | 0.84 | HTT (0.70) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8515790 | 0.82 | LMNA (0.58) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8506195 | 0.82 | HTT (0.58) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8506416 | 0.81 | SMN1; SMN2 (0.66) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL13431477 | 0.80 | SMN1; SMN2 (0.63) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8516166 | 0.79 | HTT (0.77) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL17456981 | 0.79 | SMN1; SMN2 (1.00) | HTTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9607954 | 0.78 | RAB9A (0.48) | HTTRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |