Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | GALR3 | O60755 | 2/20 | 0.71 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423236 | 0.86 | RAB9A (0.73) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8515901 | 0.85 | HTT (0.65) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17456981 | 0.83 | SMN1; SMN2 (1.00) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8506416 | 0.83 | SMN1; SMN2 (0.66) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8516267 | 0.82 | HTT (0.61) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1904097 | 0.81 | HTT (0.70) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27697481 | 0.81 | RAB9A (0.64) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5435674 | 0.81 | ICAM1 (0.60) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3342307 | 0.80 | RAB9A (0.58) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9607960 | 0.80 | NPC1 (0.57) | HTTNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |