Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973447 | 1.00 | PTGS2 (0.52) | PTGS2CES2CES1CYP2D6SRC | |
| SCHEMBL29273241 | 1.00 | PTGS2 (0.52) | PTGS2CES2CES1CYP2D6SRC | |
| SCHEMBL25287081 | 0.98 | PTGS2 (0.50) | PTGS2CES2CES1CYP2D6SRC | |
| Boric Acid SCHEMBL28990244 | 0.94 | PTGS2 (0.47) | PTGS2CES2CES1CYP2D6SRC | |
| Lithium Ion SCHEMBL30668805 | 0.90 | PTGS2 (0.44) | PTGS2CES2CES1CYP2D6SRC | |
| Lithium Ion SCHEMBL30276146 | 0.88 | PTGS2 (0.43) | PTGS2CES2CES1CYP2D6FAAH | |
| SCHEMBL11738135 | 0.87 | PTGS2 (0.71) | PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9577330 | 0.84 | CYP2C9 (0.52) | PTGS2CYP2D6LMNAMAPK1ADRB3 | |
| SCHEMBL10443247 | 0.82 | PTGS1 (0.54) | PTGS2CYP2D6LMNAPTGS1SMN1; SMN2 | |
| SCHEMBL11450473 | 0.82 | LMNA (0.50) | PTGS2LMNAADRB3HTR2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306681-A | Synthesis method of 3-oxazoline-5-ketone and derivative thereof | 湖南医药学院 | 2025-01-14 | — | — | CN | claimed |
| US-20030083380-A1 | Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging | YU RUEY J (US) | 2003-05-01 | — | — | US | claimed |
| EP-0273202-B1 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | SCOTT EUGENE J VAN (US) | 1995-06-21 | — | — | EP | claimed |
| JP-1121298-A | — | — | None | — | — | JP | disclosed |
| JP-2000294-A | — | — | None | — | — | JP | disclosed |
| US-20250369029-A1 | METHOD FOR PRODUCING AMINO ACID AND PEPTIDE COMPOUND, USING ENZYME AND ADDITIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2025-12-04 | — | — | US | disclosed |
| US-12428403-B2 | N-(heterocyclyl and heterocyclylalkyl)-3-benzylpyridin-2-amine derivatives as SSTR4 agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-09-30 | — | — | US | disclosed |
| EP-4520829-A1 | METHOD FOR PRODUCING AMINO ACID AND PEPTIDE COMPOUND, USING ENZYME AND ADDITIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-03-12 | — | — | EP | disclosed |
| CN-119156450-A | Method for producing amino acid and peptide compounds using enzymes and additives | 中外制药株式会社 | 2024-12-17 | — | — | CN | disclosed |
| CN-115485273-B | N- (heterocyclyl and heterocyclylalkyl) -3-benzyl pyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023219156-A1 | METHOD FOR PRODUCING AMINO ACID AND PEPTIDE COMPOUND, USING ENZYME AND ADDITIVE | 中外製薬株式会社 | 2023-11-16 | — | — | WO | disclosed |
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0386243-A1 | PLATINUM (II) COMPLEXES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-09-12 | — | — | EP | disclosed |
| JP-H02294-A | PLATINUM COORDINATION COMPOUND | SAGAMI CHEM RES CENTER | 1990-01-05 | — | — | JP | disclosed |
| JP-H01121298-A | PRODUCTION OF N-SUBSTITUTED-AMINO ACID DERIVATIVE | SAGAMI CHEM RES CENTER | 1989-05-12 | — | — | JP | disclosed |
| EP-0076721-B1 | PROCESS FOR THE CARBONYLATION OF SECONDARY BENZYL HALIDES | Montedison S.p.A. (IT) | 1985-02-06 | — | — | EP | disclosed |
| EP-0076721-A1 | Process for the carbonylation of secondary benzyl halides | Montedison S.p.A. (IT) | 1983-04-13 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428403-B2 | N-(heterocyclyl and heterocyclylalkyl)-3-benzylpyridin-2-amine derivatives as SSTR4 agonists | SSTR4, SSTR3, SSTR1 | PTGS2 2958/4885CES2 1741/4885CES1 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.