Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8517001 | 0.91 | ALDH1A1 (0.43) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8517010 | 0.85 | KMT2A (0.47) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516361 | 0.84 | KMT2A (0.46) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516605 | 0.83 | KMT2A (0.49) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516220 | 0.79 | BRD4 (0.47) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8368691 | 0.79 | TP53 (0.39) | KMT2AMEN1USP2ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL8517401 | 0.79 | USP2 (0.41) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8515904 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516678 | 0.77 | ALDH1A1 (0.42) | KMT2AMEN1CASP1USP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8516337 | 0.77 | LMNA (0.47) | USP2CNR2LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |