Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552421 | 0.83 | BCAT2 (0.50) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL529871 | 0.82 | BCAT2 (0.48) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL6389902 | 0.80 | BCAT2 (0.47) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL27574214 | 0.79 | BCAT2 (0.50) | BCAT2KDM4EMEN1KMT2AIKBKB | |
| SCHEMBL27911586 | 0.79 | BCAT2 (0.55) | BCAT2BRD4KDM4EMEN1KMT2A | |
| Dimethylamine SCHEMBL9280041 | 0.79 | BCAT2 (0.46) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL27942798 | 0.78 | CASP1 (0.44) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL27923730 | 0.78 | BCAT2 (0.39) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL3834197 | 0.78 | KMT2A (0.50) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL28784266 | 0.78 | BCAT2 (0.44) | BCAT2BRD4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831800-A4 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0831800-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040100-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |