Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516080 | 0.87 | USP2 (0.35) | — | |
| SCHEMBL8517087 | 0.85 | USP2 (0.34) | — | |
| SCHEMBL8367898 | 0.85 | CTSB (0.31) | — | |
| SCHEMBL8516522 | 0.85 | USP2 (0.33) | POLB | |
| SCHEMBL8516687 | 0.84 | USP2 (0.33) | PDE4BPDE4D | |
| SCHEMBL8516762 | 0.82 | CYP1A2 (0.36) | CCNT1CDK9 | |
| Trifluoroacetic Acid SCHEMBL8516655 | 0.82 | TP53 (0.36) | PDE4BPDE4DPOLB | |
| SCHEMBL8368692 | 0.80 | MAPT (0.35) | CCNT1CDK9 | |
| SCHEMBL8365258 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL8365273 | 0.79 | BRD4 (0.37) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |