Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8515708 | 0.92 | CFTR (0.46) | CFTRPOLBCNR2BRD4CA12 | |
| Trifluoroacetic Acid SCHEMBL8516484 | 0.91 | CFTR (0.45) | CFTRPOLBCNR2BRD4CA12 | |
| Trifluoroacetic Acid SCHEMBL8515718 | 0.90 | CFTR (0.44) | CFTRPOLBCNR2BRD4CA12 | |
| Trifluoroacetic Acid SCHEMBL8366714 | 0.90 | LMNA (0.43) | CFTRPOLBCNR2BRD4LMNA | |
| Trifluoroacetic Acid SCHEMBL8367871 | 0.89 | CFTR (0.46) | CFTRCA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL8516973 | 0.87 | CFTR (0.44) | CFTRPOLBCNR2BRD4CA12 | |
| Trifluoroacetic Acid SCHEMBL8516454 | 0.85 | CNR2 (0.41) | CFTRPOLBCNR2BRD4CA12 | |
| Trifluoroacetic Acid SCHEMBL8516143 | 0.84 | PAX8 (0.44) | CFTRPOLBCNR2CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL8362794 | 0.83 | CFTR (0.42) | CFTRPOLBCA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL8516150 | 0.81 | CFTR (0.47) | CFTRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |