SCHEMBL8516743

SCHEMBL8516743

Nc1c(N(c2ccccc2)c2ccccc2)cc(O)c(O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.34
EIF4H Q15056 1/20 0.34
HKDC1 Q2TB90 1/20 0.33
ALOX15 P16050 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582938 0.82 POLB (0.37) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL8582837 0.72 POLB (0.46) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL1995638 0.71 ALDH1A1 (0.54) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL16848498 0.69 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL17366525 0.69 ALOX5 (0.52) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL184114 0.69 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL5881115 0.68 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL6941899 0.68 HTT (0.35) ALDH1A1MAPTKDM4ECYP1A2CYP3A4
SCHEMBL17366527 0.67 ALOX5 (0.54) ALDH1A1MAPTKDM4EALOX15MEN1
SCHEMBL24702376 0.66 ALDH1A1 (0.36) ALDH1A1MAPTKDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1063460-C Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 2001-03-21 CN disclosed
US-5889103-A CONSISTS OF A POLYMER OF QUINONE OR DERIVATIVES, A WATER SOLUBLE POLYMER, AN INORGANIC COLLOID AND AN ALKALI METAL SILICATE; USED AS ANTISCALING AGENT IN POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS IN ALKALINE SOLUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-30 US disclosed
EP-0760378-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1999-01-27 EP disclosed
CN-1039334-C Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1998-07-29 CN disclosed
US-5728781-A POLYMERIZING AN UNSATURATED MONOMER IN A VESSEL HAVING A COATING FILM ON THE INNER WALL SURFACE THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-17 US disclosed
EP-0632058-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-01-28 EP disclosed
US-5691428-A Process for producing a polymer using a quinone compound condensation product polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-11-25 US disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0540934-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1997-02-05 EP disclosed
EP-0534434-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1996-12-11 EP disclosed
US-5457170-A Coating interior wall of vessel used for addition polymerization SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-10-10 US disclosed
US-5442017-A Addition polymerization in vessel with interior wall coating comprised of condesation product of aromatic amine, aromatic alcohol and acetone plus polymeric material and colloidal silica SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-08-15 US disclosed
US-5424003-A Preventive coatings for equipment and reactors used for addition polymerization of unsaturated compounds; antideposit agents; amino resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-06-13 US disclosed
US-5399613-A Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-03-21 US disclosed
CN-1097768-A Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1995-01-25 CN disclosed
EP-0632058-A1 Polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-01-04 EP disclosed
CN-1074685-A The medicament of preventing polymer fouling, container and application SHINETSU CHEMICAL CO (JP) 1993-07-28 CN disclosed
EP-0540934-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-12 EP disclosed
EP-0534434-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-31 EP disclosed