SCHEMBL8516764

SCHEMBL8516764

CC(C)(c1ccccc1)c1ccc(O)c(-c2cccc(S(=O)(=O)O)c2O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.45
CNR2 P34972 4/20 0.45
ESR1 P03372 4/20 0.43
ESR2 Q92731 3/20 0.43
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
NR3C2 P08235 3/20 0.38
PGAM1 P18669 1/20 0.37
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
NFKB1 P19838 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KLF10 Q13118 1/20 0.35
NPC1 O15118 1/20 0.35
PLA2G1B P04054 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SENP8 Q96LD8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8516981 0.82 NR3C2 (0.48) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL2339675 0.80 ESR1 (0.52) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8517718 0.80 PGAM1 (0.41) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8516948 0.77 ALDH1A1 (0.38) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8516810 0.76 PGAM1 (0.45) ALDH1A1PGAM1ALOX15NFKB1L3MBTL1
SCHEMBL8516809 0.76 HSD17B10 (0.46) ALDH1A1PGAM1NFKB1L3MBTL1TNNI3
SCHEMBL8370511 0.75 CNR1 (0.43) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8517108 0.74 PGAM1 (0.47) ALDH1A1PGAM1ALOX15NFKB1L3MBTL1
SCHEMBL11226795 0.74 CNR1 (0.60) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL8368894 0.74 ESR1 (0.50) CNR1CNR2ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed