Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851731 | 0.90 | MRGPRX4 (0.58) | MRGPRX4NR4A2 | |
| SCHEMBL25214512 | 0.83 | SMPD1 (0.74) | SMPD1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL30392119 | 0.83 | SMPD1 (0.74) | SMPD1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL13268612 | 0.80 | AKR1C3 (0.72) | AKR1C3 | |
| SCHEMBL851693 | 0.80 | MRGPRX4 (0.46) | MRGPRX4NR4A2XDHNR4A1NR4A3 | |
| SCHEMBL4684138 | 0.78 | MRGPRX4 (0.70) | MRGPRX4NR4A2 | |
| SCHEMBL27875417 | 0.76 | AKR1C3 (0.65) | MRGPRX4AKR1C3 | |
| SCHEMBL851678 | 0.76 | MEN1 (0.60) | SMPD1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL851559 | 0.76 | MRGPRX4 (0.49) | MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL851770 | 0.75 | AKR1C3 (0.52) | SMPD1MRGPRX4NR4A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |