Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852236 | 0.93 | MEN1 (0.69) | MEN1KMT2ARAB9AMAOBSMPD1 | |
| SCHEMBL29010786 | 0.90 | MEN1 (0.64) | MEN1KMT2ARAB9AMAOBSMPD1 | |
| SCHEMBL851730 | 0.89 | FFAR1 (0.60) | MEN1KMT2AMAOBALKBH1FFAR1 | |
| SCHEMBL851979 | 0.87 | PARP15 (0.62) | MEN1KMT2ARAB9APOLBPTGER4 | |
| SCHEMBL851692 | 0.84 | HDAC1 (0.50) | MEN1KMT2ARAB9AMAOBSMPD1 | |
| SCHEMBL851619 | 0.84 | RAB9A (0.58) | RAB9AMAOBSMPD1FFAR1RXRA | |
| SCHEMBL851694 | 0.83 | RAB9A (0.44) | MEN1KMT2ARAB9AMAOBSMPD1 | |
| SCHEMBL851521 | 0.82 | MAOB (0.58) | MEN1KMT2ARAB9AMAOBFFAR1 | |
| SCHEMBL851769 | 0.82 | MEN1 (0.51) | MEN1KMT2ARAB9AMAOBFFAR1 | |
| SCHEMBL851606 | 0.81 | PARP15 (0.55) | MEN1KMT2ARAB9APOLBPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | MEN1 258/4885KMT2A 3122/4885RAB9A 1915/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | MEN1 258/4885KMT2A 3122/4885RAB9A 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.