Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851559 | 0.92 | MRGPRX4 (0.49) | MRGPRX4NR4A2NR4A1NR4A3NPC1 | |
| SCHEMBL851679 | 0.80 | SMPD1 (0.54) | MRGPRX4NR4A2NR4A1NR4A3XDH | |
| SCHEMBL851694 | 0.79 | RAB9A (0.44) | MRGPRX4NR4A2NR4A1NR4A3NPC1 | |
| SCHEMBL851731 | 0.76 | MRGPRX4 (0.58) | MRGPRX4NR4A2RAB9AFFAR1FFAR4 | |
| SCHEMBL851560 | 0.73 | MRGPRX4 (0.43) | MRGPRX4NR4A2RAB9AFFAR1FFAR4 | |
| SCHEMBL852056 | 0.72 | PARP15 (0.44) | NPC1POLBCYP2C9RAB9AFFAR1 | |
| SCHEMBL851237 | 0.71 | RAB9A (0.44) | NPC1RAB9AFFAR1 | |
| SCHEMBL184424 | 0.70 | ANPEP (0.51) | NR4A2NR4A1NR4A3 | |
| SCHEMBL2570186 | 0.69 | LMNA (0.49) | NPC1RAB9A | |
| SCHEMBL27875417 | 0.67 | AKR1C3 (0.65) | MRGPRX4NPC1POLBCYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |