Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 12/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851679 | 0.90 | SMPD1 (0.54) | MRGPRX4NR4A2 | |
| SCHEMBL30391969 | 0.84 | NR4A2 (0.71) | MRGPRX4FFAR1FFAR4NR4A2ALKBH1 | |
| SCHEMBL25203039 | 0.84 | NR4A2 (0.71) | MRGPRX4FFAR1FFAR4NR4A2ALKBH1 | |
| SCHEMBL4684657 | 0.80 | NR4A2 (0.69) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL851559 | 0.79 | MRGPRX4 (0.49) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL851730 | 0.77 | FFAR1 (0.60) | MRGPRX4FFAR1FFAR4NR4A2ALKBH1 | |
| SCHEMBL4684138 | 0.77 | MRGPRX4 (0.70) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL851377 | 0.77 | MEN1 (0.68) | MRGPRX4FFAR1FFAR4NR4A2ALKBH1 | |
| SCHEMBL27875417 | 0.76 | AKR1C3 (0.65) | MRGPRX4RAB9A | |
| SCHEMBL851693 | 0.76 | MRGPRX4 (0.46) | MRGPRX4FFAR1FFAR4NR4A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |