Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MYB | P10242 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310776 | 0.83 | SLC2A1 (0.43) | HPGDGAAMAPTTSHRHSD17B10 | |
| SCHEMBL26208674 | 0.83 | HPGD (0.46) | HPGDPOLBGAAMAPTATM | |
| SCHEMBL3816129 | 0.81 | HPGD (0.60) | HPGDPOLBGAAMAPTMYB | |
| SCHEMBL21253838 | 0.81 | HPGD (0.49) | HPGDPOLBGAAMAPTATM | |
| SCHEMBL2201698 | 0.80 | ALDH1A1 (0.42) | HPGDMAPTTSHRHSD17B10CYP3A4 | |
| SCHEMBL20537238 | 0.80 | HPGD (0.51) | HPGDPOLBGAAMAPTTSHR | |
| SCHEMBL20554922 | 0.80 | HPGD (0.48) | HPGDPOLBGAAMAPTATM | |
| SCHEMBL5086985 | 0.80 | HPGD (0.48) | HPGDPOLBGAAMAPTATM | |
| SCHEMBL8741164 | 0.80 | L3MBTL1 (0.50) | GAAMYBTLR4ALDH1A1TDP1 | |
| SCHEMBL7128768 | 0.79 | HPGD (0.45) | HPGDPOLBGAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005151-A | Processs for preparing aromatic olefins using palladacycle catalysis | AVENTIS (DE) | 1999-12-21 | — | — | US | claimed |
| US-6005151-A | Processs for preparing aromatic olefins using palladacycle catalysis | AVENTIS (DE) | 1999-12-21 | — | — | US | disclosed |