Sugi Predict

Sugi Predict / Compounds / SCHEMBL85170

SCHEMBL85170

SCHEMBL85170

Cc1cc([N+](=O)[O-])ccc1Br

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.68
▸ CYP3A4 P08684 5/20 0.68
▸ TDP1 Q9NUW8 3/20 0.68
▸ TSHR P16473 5/20 0.67
▸ ACHE P22303 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ PTPRC P08575 1/20 0.48
▸ S100A4 P26447 1/20 0.48
▸ LMNA P02545 2/20 0.46
▸ MAPT P10636 4/20 0.46
▸ CRHBP P24387 2/20 0.46
▸ CRHR2 Q13324 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ PDE2A O00408 1/20 0.46
▸ PDE5A O76074 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ NFKB1 P19838 1/20 0.46
▸ APEX1 P27695 1/20 0.46
▸ PDE4A P27815 1/20 0.46
▸ BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648640 1.00 ALDH1A1 (0.68) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL29874193 0.83 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL113519 0.83 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL85646 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL22529929 0.81 HSPB1 (0.53) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL29351884 0.81 HSPB1 (0.53) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL3277269 0.80 PTPRC (0.54) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL30317899 0.80 PTPRC (0.54) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL384312 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1TSHRACHE
SCHEMBL29511002 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638615-A Pyridine-containing terphenyl diamine, colorless transparent polyimide, and preparation methods and applications thereof 华南理工大学 2025-03-18 — — CN claimed
CN-117843499-A Diamine with asymmetric structure, high-performance polyimide, and preparation methods and applications thereof 华南理工大学 2024-04-09 — — CN claimed
CN-113150273-B Preparation method of nitrogen-containing polymer 中国科学院福建物质结构研究所 2024-01-23 — — CN claimed
CN-114411169-B Photoelectrocatalysis hydrogen production and nitroarene in-situ hydrogenation integrated device and application 山西大学 2023-12-26 — — CN claimed
CN-114411169-A Photoelectrocatalysis hydrogen production and nitro aromatic hydrocarbon in-situ hydrogenation integrated device and application 山西大学 2022-04-29 — — CN claimed
CN-113150273-A Preparation method of nitrogen-containing polymer 中国科学院福建物质结构研究所 2021-07-23 — — CN claimed
CN-106883175-A A kind of preparation method of tolvaptan 天津泰普制药有限公司 2017-06-23 — — CN claimed
CN-102219800-B Organic substituted boric acid ester, boron affinity functional material using organic substituted boric acid ester as functional monomer as well as preparation and application of organic substituted boric acid ester NANJING UNIVERSITY OF TECHNOLOGY 2015-02-25 — — CN claimed
CN-102219800-A Organic substituted boric acid ester, boron affinity functional material using organic substituted boric acid ester as functional monomer as well as preparation and application of organic substituted boric acid ester NANJING UNIVERSITY OF TECHNOLOGY 2011-10-19 — — CN claimed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 — — US disclosed
EP-4711366-A1 PYRIMIDO MACROHETEROCYCLIC COMPOUND AS WEE1-YES DUAL-TARGET INHIBITOR AND USE THEREOF Mindrank AI Ltd. (CN) 2026-03-18 — — EP disclosed
US-12473296-B2 Perk inhibiting compounds HIBERCELL, INC. (US) 2025-11-18 — — US disclosed
EP-4642767-A1 PYRIMIDINE CARBOXAMIDE COMPOUNDS Acrivon Therapeutics, Inc. (US) 2025-11-05 — — EP disclosed
EP-4619406-A1 TRICYCLIC COMPOUNDS Schrödinger, Inc. (US) 2025-09-24 — — EP disclosed
EP-0396943-A2 Optical storage medium and storage process NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-11-14 — — EP disclosed
US-4957976-A IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1990-09-18 — — US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 — — EP disclosed
EP-0270071-A2 Process for preparing modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-08 — — EP disclosed
EP-0124283-A1 Process for the preparation of benzoyl ureas UNION CARBIDE CORPORATION (US) 1984-11-07 — — EP disclosed
US-4287372-A Preparation of nitro-substituted diphenyl ethers UOP INC. (US) 1981-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 ALDH1A1 1008/4885CYP3A4 27/4885TDP1 2058/4885
US-12473296-B2 Perk inhibiting compounds MAPK1, ERN1, MAP3K20 ALDH1A1 1102/4885CYP3A4 2620/4885TDP1 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.