Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874193 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL8508219 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1CYP3A4ALOX15 | |
| SCHEMBL6626692 | 0.84 | PTGS2 (0.51) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL85170 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL30648640 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL30317899 | 0.80 | PTPRC (0.54) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL3277269 | 0.80 | PTPRC (0.54) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL29511002 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL384312 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1CYP3A4ACHE | |
| SCHEMBL11050883 | 0.78 | PTPRC (0.57) | ALDH1A1TSHRTDP1CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850258-B | Synthesis method of masitinib | 东北林业大学 | 2024-09-24 | — | — | CN | claimed |
| CN-115850258-A | Synthesis method of masitinib | 东北林业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-113278304-B | Double-ratio type hemicyanine dye molecule, and synthesis method and application thereof | 广西师范大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113278304-A | Double-ratio type hemicyanine dye molecule, and synthesis method and application thereof | 广西师范大学 | 2021-08-20 | — | — | CN | claimed |
| CN-105503493-A | Synthesis method for flavonoid compound drug intermediate 1,1-diphenyl-1-propylene | CHENGDU QIANYE LONGHUA PETROLEUM ENG TECH CONSULTING CO LTD | 2016-04-20 | — | — | CN | claimed |
| EP-0396943-B1 | Optical storage medium and storage process | NIPPON TELEGRAPH & TELEPHONE (JP) | 1995-07-05 | — | — | EP | claimed |
| US-5124944-A | OPTICAL STORAGE MEDIUM AND STORAGE PROCESS | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1992-06-23 | — | — | US | claimed |
| EP-0396943-A2 | Optical storage medium and storage process | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1990-11-14 | — | — | EP | claimed |
| US-4734532-A | HIGH SPEED OXIDATIVE DIMERIZATION OF 4-NITROTOLUENE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | claimed |
| EP-4105213-B1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND THERAPEUTIC PHARMACEUTIC COMPOSITION COMPRISING SAME | PHAROS IBIO CO LTD (KR) | 2026-04-15 | — | — | EP | disclosed |
| US-20260070903-A1 | NOVEL PYRIDO[3,4-D]PYRIMIDIN-8-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING CANCER, COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-12 | — | — | US | disclosed |
| US-12404274-B2 | Macrocycles as factor xia inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| US-12398142-B2 | Abelson non-tyrosine kinase compounds for the treatment of neurodegenerative diseases | EMORY UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| CN-119585242-A | RAF kinase inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-0078768-A1 | Process for the catalytic Pd arylation of olefines with aryl halogenides | CIBA-GEIGY AG (CH) | 1983-05-11 | — | — | EP | disclosed |
| EP-0017455-B1 | LINEAR CRYSTALLINE ALPHA-ALKYLPOLYBENZYLS AND PROCESS FOR PREPARING THEM | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4259475-A | FRIEDEL-CRAFTS COMPLEX CATALYST | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-03-31 | — | — | US | disclosed |
| EP-0017455-A1 | Linear crystalline alpha-alkylpolybenzyls and process for preparing them | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4212824-A | PLATINUM, IRON OXIDE OR HYDROXIDE ON CARBON BLACK | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4126626-A | DYES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404274-B2 | Macrocycles as factor xia inhibitors | TFPI, TFPI2, F11 | ALDH1A1 4598/4885TSHR 2404/4885TDP1 2393/4885 |
| US-12398142-B2 | Abelson non-tyrosine kinase compounds for the treatment of neurodegenerative diseases | ABL2, ABL1, FYN | ALDH1A1 3669/4885TSHR 3907/4885TDP1 647/4885 |
| US-20260070903-A1 | NOVEL PYRIDO[3,4-D]PYRIMIDIN-8-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING CANCER, COMPRISING SAME | CCNC, CKS1B, CKS2 | ALDH1A1 2140/4885TSHR 3614/4885TDP1 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.