Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759814 | 0.79 | SLC2A1 (0.51) | KDM4ESLC2A1ALDH1A1HSD17B10CYP2A13 | |
| SCHEMBL14161794 | 0.76 | MAPT (0.48) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2228615 | 0.75 | SMN1; SMN2 (0.48) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL12531879 | 0.75 | ADORA3 (0.46) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11022519 | 0.74 | DRD3 (0.49) | KDM4EALDH1A1HSD17B10HPGDDRD4 | |
| SCHEMBL14161884 | 0.73 | MAPT (0.48) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18837935 | 0.72 | SLC2A1 (0.44) | KDM4ESLC2A1ALDH1A1HSD17B10CYP2A13 | |
| SCHEMBL6532353 | 0.71 | ALDH1A1 (0.43) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL14161883 | 0.70 | MAPT (0.56) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11193326 | 0.70 | CYP2A13 (0.75) | GAAKDM4EALDH1A1HSD17B10CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547708-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-02-26 | — | — | EP | disclosed |