SCHEMBL8517434

SCHEMBL8517434

CCOC(=O)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
NR1I2 O75469 1/20 0.43
PGR P06401 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
PTGS2 P35354 1/20 0.43
PDE4D Q08499 1/20 0.43
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRPA1 O75762 1/20 0.40
DGKA P23743 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11878749 0.94 CYP1A2 (0.52) CYP1A2NR1I2PGRADORA3PTGS2
SCHEMBL3682278 0.88 CYP1A2 (0.47) CYP1A2NR1I2PGRADORA3PTGS2
SCHEMBL10180372 0.86 CYP1A2 (0.44) CYP1A2NR1I2PGRADORA3PTGS2
SCHEMBL29663869 0.86 CYP1A2 (0.44) CYP1A2NR1I2PGRADORA3PTGS2
Succinic Acid Diethyl Ester SCHEMBL17783729 0.85 CYP1A2 (0.61) CYP1A2NR1I2PGRADORA3PTGS2
SCHEMBL29165577 0.85 DGKA (0.52) CYP1A2ALDH1A1DGKA
SCHEMBL27628460 0.84 CYP1A2 (0.53) CYP1A2NR1I2PGRADORA3PTGS2
SCHEMBL22817577 0.84 TSHR (0.54) CYP1A2GAAALDH1A1TSHRL3MBTL1
SCHEMBL453986 0.83 LTA4H (0.44) CYP1A2GAAMGAMSIMGAM2
SCHEMBL18334313 0.83 CYP1A2 (0.41) CYP1A2NR1I2PGRADORA3PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8325276-A None JP disclosed
US-6001739-A Method of manufacturing a semiconductor device TOKYO ELECTRON LIMITED (JP) 1999-12-14 US disclosed
JP-H08325276-A NEW ALKOXYSILANE COMPOUND AND ITS USE MITSUBISHI MATERIALS CORP 1996-12-10 JP disclosed