Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517278 | 0.85 | THRB (0.42) | NR1H2NR1H3MGLLLPLLIPG | |
| SCHEMBL8382588 | 0.77 | TP53 (0.40) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL73339 | 0.75 | ALDH1A1 (0.33) | TSHRL3MBTL1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL3481645 | 0.72 | TP53 (0.43) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL5512042 | 0.72 | NR1H2 (0.33) | NR1H2NR1H3MAPT | |
| SCHEMBL3482281 | 0.70 | TP53 (0.42) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL3482376 | 0.70 | TDP1 (0.46) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL4556361 | 0.68 | ALDH1A1 (0.58) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL11575427 | 0.67 | TSHR (0.32) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL14579977 | 0.67 | TP53 (0.48) | TSHRMAPK1ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905567-A1 | HOLE TRANSPORTING MATERIAL | OSAKA GAS CO., LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |