Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744190 | 0.82 | TSHR (0.35) | TSHRDNM1ZDHHC20ALDH1A1CNR1 | |
| SCHEMBL27797457 | 0.79 | DNM1 (0.41) | TSHRDNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL16061313 | 0.77 | DNM1 (0.44) | TSHRDNM1EPHX1ADH1BADH1C | |
| SCHEMBL8744213 | 0.76 | TSHR (0.37) | TSHRZDHHC20HPGD | |
| SCHEMBL5634635 | 0.74 | DNM1 (0.41) | TSHRDNM1EPHX1ADH1BADH1C | |
| SCHEMBL27816517 | 0.74 | ALDH1A1 (0.45) | DNM1ALDH1A1CNR1CNR2EPHX1 | |
| SCHEMBL31252977 | 0.73 | DNM1 (0.44) | TSHRDNM1LPAR1LPAR3HPGD | |
| SCHEMBL11732153 | 0.73 | DNM1 (0.40) | TSHRDNM1EPHX1ADH1BADH1C | |
| SCHEMBL11293584 | 0.73 | LPAR1 (0.49) | DNM1EPHX1ADH1BADH1CADH1A | |
| SCHEMBL9854525 | 0.73 | ALDH1A1 (0.40) | TSHRDNM1ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661310-B1 | Cyclo-olefincopolymers and process for their preparation | TICONA GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0661308-B1 | Cyclo-olefin copolymers and process for their preparation | TICONA GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0661310-A2 | Cyclo-olefincopolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661308-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |