Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27816517 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CNR1CNR2MAPTMEN1 | |
| SCHEMBL13354395 | 0.81 | ADH1B (0.41) | MAPTDNM1SMN1; SMN2TSHRTRPA1 | |
| SCHEMBL27797457 | 0.80 | DNM1 (0.41) | ALDH1A1CNR1CNR2DNM1SMN1; SMN2 | |
| SCHEMBL11498364 | 0.80 | TSHR (0.40) | ALDH1A1DNM1SMN1; SMN2TSHR | |
| SCHEMBL18506725 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL18506731 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL16061313 | 0.79 | DNM1 (0.44) | DNM1SMN1; SMN2TSHRLPAR1LPAR3 | |
| SCHEMBL10711373 | 0.76 | ALDH1A1 (0.36) | ALDH1A1CNR1CNR2MAPTHTT | |
| SCHEMBL11808895 | 0.76 | TSHR (0.45) | ALDH1A1MAPTDNM1SMN1; SMN2TSHR | |
| SCHEMBL9044982 | 0.76 | TSHR (0.36) | SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |