Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519377 | 0.92 | BRD4 (0.39) | HDAC1AKT1PDCD1CD274KCNA5 | |
| SCHEMBL8139001 | 0.67 | L3MBTL1 (0.49) | HDAC1NAMPTALDH1A1 | |
| SCHEMBL7394047 | 0.67 | NAMPT (0.49) | NAMPTITGB3ITGAVSCN9APDCD1 | |
| SCHEMBL28619767 | 0.66 | HDAC1 (0.50) | HDAC1NAMPT | |
| SCHEMBL7551243 | 0.65 | L3MBTL1 (0.51) | HDAC1NAMPTHDAC10HDAC6LMNA | |
| SCHEMBL16192946 | 0.64 | NPC1 (0.58) | HDAC1NAMPTHDAC10HDAC6CTSK | |
| SCHEMBL31609036 | 0.64 | NAMPT (0.52) | HDAC1NAMPTHDAC10HDAC6POLB | |
| SCHEMBL8372079 | 0.62 | L3MBTL1 (0.56) | HDAC1NAMPTHDAC10HDAC6CTSK | |
| SCHEMBL3180689 | 0.62 | L3MBTL1 (0.61) | HDAC1NAMPTHDAC10HDAC6CTSK | |
| SCHEMBL21996778 | 0.62 | POLB (0.51) | HDAC1NAMPTAKT1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |