SCHEMBL8518340

SCHEMBL8518340

C=CC(=O)OCCCCCCCCCCCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(OCCCCCCCCCCCOC(=O)C=C)cc3O)n2)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
HTT P42858 1/20 0.40
PTPN11 Q06124 3/20 0.40
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC10 Q969S8 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC9 Q9UKV0 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
MAPT P10636 3/20 0.37
NPSR1 Q6W5P4 3/20 0.37
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383344 1.00 THRB (0.48) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL30887136 1.00 THRB (0.48) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL2240459 0.93 THRB (0.56) THRBTSHRPTPN11MAPTNPSR1
SCHEMBL29512550 0.93 THRB (0.56) THRBTSHRPTPN11MAPTNPSR1
SCHEMBL8909788 0.92 TSHR (0.49) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL13897527 0.91 THRB (0.54) THRBTSHRHDAC3HDAC4HDAC1
SCHEMBL19466502 0.86 ALOX15 (0.48) TSHRPTPN11HDAC3HDAC4HDAC1
SCHEMBL19466444 0.84 POLB (0.56) TSHRHTTPTPN11HDAC3HDAC4
SCHEMBL30887153 0.84 POLB (0.56) TSHRHTTPTPN11HDAC3HDAC4
SCHEMBL8975634 0.84 POLB (0.56) TSHRHTTPTPN11HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074814-A9 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE THEREOF SUBLINO LIMITED (GB) 2025-05-22 WO disclosed
WO-2024074814-A1 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE SUBLINO LIMITED (GB) 2024-04-11 WO disclosed
US-5869588-A UV ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 US disclosed
US-5672704-A ULTRAVIOLET RADIATION STABILIZERS CIBA-GEIGY CORPORATION 1997-09-30 US disclosed
US-5538840-A SILVER HALIDE EMULSIONS AND POLYMERS ON SUBSTRATES WITH TRIAZINE PHENOLS CIBA-GEIGY CORPORATION (US) 1996-07-23 US disclosed
EP-0706083-A1 Photographic recording material containing an UV-absorber CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed