SCHEMBL8518374

SCHEMBL8518374

COc1ccc(P(=O)(O)O)c(C=O)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.59
TRIM24 O15164 1/20 0.54
TYR P14679 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
ALDH1A1 P00352 8/20 0.51
KDM4E B2RXH2 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 1/20 0.43
JUN P05412 1/20 0.41
NFKB1 P19838 1/20 0.41
CYP2A6 P11509 1/20 0.41
LMNA P02545 1/20 0.40
CYP2C9 P11712 1/20 0.40
SRC P12931 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388387 0.77 SRC (0.56) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL9355693 0.77 CA12 (0.52) ALDH1A1CYP1A2MAPTRAB9ALMNA
SCHEMBL29957021 0.75 ALDH1A1 (0.70) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL12672585 0.75 ALDH1A1 (0.70) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL29559365 0.74 ERN1 (1.00) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL120412 0.74 ERN1 (1.00) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL10213815 0.74 ERN1 (0.61) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL10722001 0.73 ACP3 (0.40) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL20339337 0.73 ERN1 (0.96) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL31026013 0.73 ERN1 (0.65) ERN1TRIM24TYRTRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed