Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597573 | 0.72 | KMT2A (0.40) | KMT2ACRHR1MAPT | |
| Hydrochloric Acid SCHEMBL7868719 | 0.64 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL23996108 | 0.62 | TYK2 (0.40) | CRHR1NAMPTKITMAPK14 | |
| SCHEMBL23996106 | 0.61 | TYK2 (0.39) | CRHR1NAMPTKITMAPK14 | |
| SCHEMBL23996109 | 0.58 | TYK2 (0.40) | CRHR1NAMPTKITMAPK14 | |
| SCHEMBL23471410 | 0.57 | KDM4E (0.60) | KDM4ENAMPT | |
| SCHEMBL23471393 | 0.56 | KDM4E (0.64) | KDM4ENAMPT | |
| SCHEMBL1004037 | 0.56 | ALDH1A1 (0.63) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL14117366 | 0.56 | SMN1; SMN2 (0.49) | LMNAKDM4E | |
| SCHEMBL936681 | 0.55 | SCD (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973152-A | Certain pyrazole derivatives as corticotropin-releasing factor receptor CRF1 specific ligands | NEUROGEN CORPORATION | 1999-10-26 | — | — | US | disclosed |