Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518449 | 1.00 | HSD17B3 (0.31) | HSD17B3CCR2HSD17B10 | |
| SCHEMBL11287172 | 0.77 | GAA (0.30) | — | |
| SCHEMBL1073591 | 0.76 | SLC6A2 (0.35) | CCR2 | |
| SCHEMBL1073590 | 0.76 | SLC6A2 (0.35) | CCR2 | |
| SCHEMBL11569817 | 0.76 | SLC6A2 (0.35) | CCR2 | |
| SCHEMBL22996132 | 0.75 | GAA (0.33) | — | |
| SCHEMBL12079378 | 0.72 | NR3C1 (0.37) | HSD17B3 | |
| SCHEMBL11577452 | 0.71 | GAA (0.30) | — | |
| SCHEMBL11576962 | 0.71 | GAA (0.30) | — | |
| SCHEMBL8518899 | 0.70 | OPRM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939551-A | Process for producing 4a-aryldecahydroisoquinoline derivatives | TORAY INDUSTRIES, INC. (JP) | 1999-08-17 | — | — | US | claimed |
| EP-0845460-A1 | PROCESS FOR PRODUCING 4a-ARYLDECAHYDROISOQUINOLINE DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1998-06-03 | — | — | EP | claimed |
| US-5939551-A | Process for producing 4a-aryldecahydroisoquinoline derivatives | TORAY INDUSTRIES, INC. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0845460-A1 | PROCESS FOR PRODUCING 4a-ARYLDECAHYDROISOQUINOLINE DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1998-06-03 | — | — | EP | disclosed |