Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL8519748 | 0.98 | PAOX (0.54) | PAOXDNM1KDM4EALDH1A1TSHR | |
| Lactic Acid SCHEMBL5425195 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Acetic Acid SCHEMBL28970281 | 0.85 | PAOX (0.66) | PAOXDNM1KDM4EALDH1A1TSHR | |
| Lactic Acid SCHEMBL23174633 | 0.85 | DNM1 (0.60) | DNM1ALDH1A1TSHRGPR84FFAR1 | |
| Lactic Acid SCHEMBL29600390 | 0.85 | DNM1 (0.60) | DNM1ALDH1A1TSHRGPR84FFAR1 | |
| Lactic Acid SCHEMBL5934076 | 0.85 | DNM1 (0.60) | DNM1ALDH1A1TSHRGPR84FFAR1 | |
| Lactic Acid SCHEMBL4093963 | 0.84 | PAOX (0.53) | PAOXDNM1KDM4EALDH1A1TDP1 | |
| Myralact SCHEMBL2734628 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL4394698 | 0.81 | DNM1 (0.64) | PAOXDNM1ALDH1A1TSHRTDP1 | |
| SCHEMBL18361393 | 0.81 | DNM1 (0.64) | PAOXDNM1ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927019-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998048768-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |