Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290254 | 0.77 | GLA (0.37) | ADORA2AGLA | |
| SCHEMBL8998740 | 0.77 | GLA (0.37) | ADORA2AGLA | |
| SCHEMBL22018447 | 0.70 | GLA (0.36) | ADORA2AGLA | |
| SCHEMBL11500330 | 0.70 | — | — | |
| SCHEMBL28988139 | 0.69 | ADORA3 (0.34) | KDM4E | |
| SCHEMBL11879772 | 0.67 | ADORA2A (0.52) | ADORA2AGLAKDM4E | |
| SCHEMBL2139234 | 0.66 | — | — | |
| SCHEMBL7083112 | 0.64 | PARP1 (0.47) | KDM4E | |
| SCHEMBL8546354 | 0.64 | — | — | |
| SCHEMBL28805611 | 0.63 | KDM4E (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612736-B1 | Process for the preparation of oxazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-04-14 | — | — | EP | claimed |
| EP-0859001-A1 | Preparation of oxazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-08-19 | — | — | EP | disclosed |