Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | NOS3 | P29474 | 5/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399142 | 0.91 | AKR1B1 (0.41) | AKR1B1LTB4R2 | |
| SCHEMBL8400340 | 0.90 | AKR1B1 (0.46) | AKR1B1 | |
| SCHEMBL8395521 | 0.89 | AKR1B1 (0.40) | AKR1B1HDAC6RXRARXRBRXRG | |
| SCHEMBL8400418 | 0.89 | RAB9A (0.40) | AKR1B1LTB4R2RXRARXRBRXRG | |
| SCHEMBL8396237 | 0.88 | SMN1; SMN2 (0.40) | AKR1B1HDAC6NOS2NOS3LTB4R2 | |
| SCHEMBL8397960 | 0.88 | AKR1B1 (0.41) | AKR1B1HDAC6LTB4R2 | |
| SCHEMBL8398941 | 0.88 | AKR1B1 (0.39) | AKR1B1LTB4R2 | |
| SCHEMBL8396084 | 0.87 | AKR1A1 (0.46) | AKR1B1 | |
| SCHEMBL8396327 | 0.87 | AKR1B1 (0.37) | AKR1B1HDAC6LTB4R2 | |
| SCHEMBL8400428 | 0.87 | AKR1B1 (0.41) | AKR1B1HDAC6LTB4R2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |