SCHEMBL8519251

SCHEMBL8519251

CCCc1cccc2c1O[B]O2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.34
DAO P14920 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520073 0.85 GABRA1 (0.40) MTNR1AELANE
SCHEMBL8600153 0.80 PRKCI (0.33)
SCHEMBL8557291 0.77 ALDH1A1 (0.39)
SCHEMBL8520143 0.76
SCHEMBL138232 0.76 AHR (0.38) MTNR1ADAOELANE
SCHEMBL8601609 0.76 ALDH1A1 (0.42)
SCHEMBL19772837 0.72 MTNR1A (0.45) MTNR1A
SCHEMBL8519249 0.70 MTNR1A (0.37) MTNR1ADAOELANE
SCHEMBL10244178 0.70 MTNR1A (0.59) MTNR1A
SCHEMBL8518761 0.70 CYP2A6 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed