SCHEMBL8519405

SCHEMBL8519405

CCc1ccc(CC)c2c1O[B]O2

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.37
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
TP53 P04637 1/20 0.32
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600153 0.80 PRKCI (0.33)
SCHEMBL8520073 0.78 GABRA1 (0.40) GABRA1GABRB2TP53
SCHEMBL8519453 0.77
SCHEMBL13082449 0.70 CTRC (0.38) CTRCGABRA1GABRB2ALDH1A1
SCHEMBL8519429 0.69 HSPA5 (0.31) TP53
SCHEMBL8519403 0.68 CTRC (0.37) CTRCGABRA1GABRB2
SCHEMBL8520143 0.65
SCHEMBL15896713 0.62 NQO2 (0.34) CTRC
SCHEMBL166573 0.61 GABRA1 (0.41) CTRCGABRA1GABRB2TP53ALDH1A1
SCHEMBL29619533 0.61 GABRA1 (0.41) CTRCGABRA1GABRB2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed