SCHEMBL8519429

SCHEMBL8519429

CCc1cc(CC)c2c(c1)O[B]O2

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8601609 0.78 ALDH1A1 (0.42)
SCHEMBL8557291 0.73 ALDH1A1 (0.39)
SCHEMBL8519608 0.71 CYP2A6 (0.40) MEN1KMT2ATP53
SCHEMBL8519427 0.71 HSPA5 (0.30) HSPA5MEN1KMT2A
SCHEMBL26113482 0.67 PARP1 (0.40) MEN1KMT2A
SCHEMBL1760666 0.63 DHFR (0.44) HSPA5MEN1KMT2AGAATP53
SCHEMBL2228767 0.63 HSPA5 (0.39) HSPA5MEN1KMT2AGAATP53
SCHEMBL18244029 0.63 HSPA5 (0.39) HSPA5MEN1KMT2AGAATP53
SCHEMBL27495245 0.63 HSPA5 (0.39) HSPA5MEN1KMT2AGAATP53
SCHEMBL8519251 0.62 MTNR1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed