Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.39 |
| ▸ | WNT3A | P56704 | 4/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480896 | 0.78 | ALDH1A1 (0.41) | HTTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL7484284 | 0.77 | HSD17B3 (0.35) | L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL6584861 | 0.67 | ERCC5 (0.39) | CTNNB1WNT3AERCC5FEN1BCHE | |
| SCHEMBL11813934 | 0.66 | KMT2A (0.62) | HTTL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8735550 | 0.62 | ERCC5 (0.74) | CTNNB1WNT3AERCC5FEN1L3MBTL1 | |
| SCHEMBL30089517 | 0.62 | CTNNB1 (0.68) | CTNNB1WNT3AERCC5FEN1L3MBTL1 | |
| SCHEMBL15979740 | 0.62 | CTNNB1 (0.68) | CTNNB1WNT3AERCC5FEN1L3MBTL1 | |
| SCHEMBL13161999 | 0.61 | ALDH1A1 (0.60) | HTTL3MBTL1MEN1RAB9AKMT2A | |
| SCHEMBL31901342 | 0.61 | ERCC5 (0.60) | CTNNB1WNT3AERCC5FEN1L3MBTL1 | |
| SCHEMBL3704844 | 0.61 | ERCC5 (0.60) | CTNNB1WNT3AERCC5FEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |