Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592097 | 0.83 | EED (0.38) | EEDHTR2AHRH1MAPTNPSR1 | |
| SCHEMBL6587141 | 0.82 | HTR2A (0.50) | EEDHTR2AHRH1MAPTLMNA | |
| SCHEMBL6587862 | 0.80 | EED (0.40) | EEDHTR2AHRH1MAPTNPSR1 | |
| SCHEMBL6586680 | 0.76 | OPRM1 (0.41) | EEDHTR2AMAPTNPSR1LMNA | |
| Maleic Acid SCHEMBL8433458 | 0.74 | HRH1 (0.42) | HTR2AHRH1LMNAKDM4EMEN1 | |
| Fumaric Acid SCHEMBL8433463 | 0.74 | HRH1 (0.42) | HTR2AHRH1LMNAKDM4EMEN1 | |
| Fumaric Acid SCHEMBL6589530 | 0.74 | SLC6A2 (0.42) | HTR2ALMNAKDM4EMEN1KMT2A | |
| Maleic Acid SCHEMBL6589525 | 0.74 | SLC6A2 (0.42) | HTR2ALMNAKDM4EMEN1KMT2A | |
| SCHEMBL6591541 | 0.72 | TIPARP (0.43) | EEDMAPTNPSR1LMNARGS12 | |
| Maleic Acid SCHEMBL6589717 | 0.71 | SLC6A2 (0.39) | HTR2AMAPTNPSR1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869502-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDER, STUTTERING, TRICHOTILLOMANIA | HOECHST MARION ROUSSEL INC. (US) | 1999-02-09 | — | — | US | disclosed |