SCHEMBL8520017

SCHEMBL8520017

NC(=O)CC(=O)CN(CC(=O)CC(N)=O)C(N)=O

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL11430358 0.85 LMNA (0.39) ALDH1A1LMNAALOX15HSD17B10
Acrylic Acid SCHEMBL11428507 0.80 LMNA (0.33) ALDH1A1LMNAALOX15HSD17B10
SCHEMBL4449358 0.79 MAPT (0.32) KDM4EGMNNUSP2ALDH1A1LMNA
SCHEMBL5481394 0.73 LMNA (0.44) KDM4EGMNNUSP2ALDH1A1LMNA
SCHEMBL7622686 0.70 ALDH1A1 (0.35) KDM4EALDH1A1LMNACYP3A4HPGD
SCHEMBL4657392 0.69 HAO1 (0.39) KDM4EGMNNUSP2ALDH1A1LMNA
SCHEMBL29625512 0.69 KDM4E (0.36) KDM4EGMNNUSP2ALDH1A1LMNA
SCHEMBL10002665 0.69 TDP1 (0.43) KDM4ELMNACYP1A2ALOX15CYP2C19
SCHEMBL13685451 0.69 TDP1 (0.33) KDM4ELMNAALOX15CYP2C19BLM
SCHEMBL15266660 0.67 ALDH1A1 (0.33) KDM4EGMNNUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229505-A WEAR LAYERS FOR FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1980-10-21 US claimed
US-4221902-A CROSSLINKED, WEAR LAYER COATINGS ARMSTRONG CORK COMPANY (US) 1980-09-09 US claimed
US-4218515-A FOR FLOOR COVERINGS HECKLES JOHN S 1980-08-19 US claimed
US-5969046-A USING TERTIARY AMINES AND EPOXIDES AS MAIN ACTIVATOR OF MICHAEL CONDENSATION CURE PROCESS ROHM AND HAAS COMPANY (US) 1999-10-19 US disclosed
EP-0580328-B1 Methacrylate functional polyesters ROHM & HAAS (US) 1997-04-02 EP disclosed
EP-0376590-B1 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM & HAAS (US) 1994-11-30 EP disclosed
EP-0580328-A2 Methacrylate functional polyesters ROHM AND HAAS COMPANY (US) 1994-01-26 EP disclosed
EP-0326723-B1 METHOD FOR REACTING TWO COMPONENTS, COMPOSITIONS, COATING COMPOSITIONS AND USES THEREOF ROHM AND HAAS COMPANY (US) 1993-03-24 EP disclosed
US-5021511-A Reacted with carbon-michael addition acceptor; coatings, adhesives, caulks, mastics; nonhydrolyzing ROHM AND HAAS COMPANY (US) 1991-06-04 US disclosed
EP-0376590-A2 Monomer or polymer composition derived from acryloxy alkyl cyanoacetamides ROHM AND HAAS COMPANY (US) 1990-07-04 EP disclosed
EP-0326723-A1 Method for reacting two components, compositions, coating compositions and uses thereof ROHM AND HAAS COMPANY (US) 1989-08-09 EP disclosed
US-4233239-A USED TO MAKE CROSSLINKED COPOLYMERS WITH ACRYLATES AND DIACETOACETAMIDES ARMSTRONG CORK COMPANY (US) 1980-11-11 US disclosed
US-4233239-A USED TO MAKE CROSSLINKED COPOLYMERS WITH ACRYLATES AND DIACETOACETAMIDES ARMSTRONG CORK COMPANY (US) 1980-11-11 US disclosed
US-4229505-A WEAR LAYERS FOR FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1980-10-21 US disclosed
US-4229505-A WEAR LAYERS FOR FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1980-10-21 US disclosed
US-4221902-A CROSSLINKED, WEAR LAYER COATINGS ARMSTRONG CORK COMPANY (US) 1980-09-09 US disclosed
US-4221902-A CROSSLINKED, WEAR LAYER COATINGS ARMSTRONG CORK COMPANY (US) 1980-09-09 US disclosed
US-4218515-A FOR FLOOR COVERINGS HECKLES JOHN S 1980-08-19 US disclosed
US-4218515-A FOR FLOOR COVERINGS HECKLES JOHN S 1980-08-19 US disclosed