Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | PRKACG | P22612 | 2/20 | 0.39 |
| ▸ | PRKACB | P22694 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 3/20 | 0.35 |
| ▸ | DDO | Q99489 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729103 | 0.84 | GPR35 (0.50) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL29638854 | 0.84 | GPR35 (0.50) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL29638857 | 0.84 | SRC (0.48) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL366714 | 0.84 | GPR35 (0.50) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL435044 | 0.84 | SRC (0.48) | SRCPRKACAPRKACGPRKACBGPR35 | |
| Bromide SCHEMBL8431246 | 0.82 | GPR35 (0.48) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL9442095 | 0.80 | GPR35 (0.69) | GPR35DAOKDM4EALDH1A1MAPT | |
| Bromide SCHEMBL9788685 | 0.80 | GPR35 (0.47) | SRCPRKACAPRKACGPRKACBGPR35 | |
| SCHEMBL15730605 | 0.76 | ATM (0.43) | SRCPRKACAPRKACGPRKACBATM | |
| SCHEMBL11682246 | 0.76 | CYP2A6 (0.44) | GPR35CYP2A6KEAP1DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |