Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.69 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49512 | 0.83 | GPR35 (1.00) | GPR35PIN1SMAD3EIF4A3CA12 | |
| SCHEMBL9510926 | 0.82 | GPR35 (0.44) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL8520252 | 0.80 | SRC (0.39) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL7040376 | 0.80 | GPR35 (0.73) | GPR35PIN1SMAD3EIF4A3CA12 | |
| SCHEMBL435044 | 0.78 | SRC (0.48) | GPR35KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL29638857 | 0.78 | SRC (0.48) | GPR35KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9279858 | 0.75 | GPR35 (0.75) | GPR35PIN1SMAD3EIF4A3CA12 | |
| SCHEMBL7682186 | 0.74 | GPR35 (0.63) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL31335635 | 0.73 | CSNK2A1 (0.43) | KDM4EHPGDHSD17B10F7F3 | |
| SCHEMBL24149191 | 0.71 | GPR35 (0.69) | GPR35PIN1SMAD3EIF4A3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180396-A | Process for dyeing keratinous fibres with oxidation dyes combined with indole derivatives and dyeing composition employed | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |