Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.72 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520473 | 0.90 | PTGIR (0.89) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8411068 | 0.83 | PTGIR (1.00) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8410718 | 0.82 | PTGIR (0.90) | PTGIRTBXAS1 | |
| SCHEMBL8411300 | 0.81 | PTGIR (0.85) | PTGIRTBXAS1 | |
| SCHEMBL8413356 | 0.80 | PTGIR (0.89) | PTGIRTBXAS1 | |
| SCHEMBL8520475 | 0.79 | PTGIR (0.70) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8411096 | 0.78 | PTGIR (0.90) | PTGIRTBXAS1 | |
| SCHEMBL8858482 | 0.77 | PTGIR (0.61) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9014526 | 0.76 | TBXAS1 (0.63) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8411294 | 0.76 | PTGIR (0.57) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |