Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309185 | 0.72 | L3MBTL1 (0.70) | GPR84HTTLMNAL3MBTL1MEN1 | |
| SCHEMBL23118869 | 0.72 | KMT2A (0.58) | HTTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29319384 | 0.72 | TAAR1 (0.39) | L3MBTL1MEN1KMT2ATAAR1TTBK1 | |
| SCHEMBL22957171 | 0.70 | — | — | |
| SCHEMBL26267972 | 0.69 | TAAR1 (0.60) | GPR84LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL22894337 | 0.69 | MAPT (0.65) | GPR84LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL28625506 | 0.69 | MAPT (0.57) | GPR84HTTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5539704 | 0.69 | GPR84 (0.50) | GPR84HTTLMNAL3MBTL1MEN1 | |
| SCHEMBL22196935 | 0.69 | HDAC3 (0.44) | GPR84HTTLMNAKMT2ATAAR1 | |
| SCHEMBL3907319 | 0.68 | L3MBTL1 (0.70) | GPR84HTTLMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946549-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027087-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |